Epigenetic transmission of piRNAs through the female germline

Sergey Shpiz; Alla Kalmykova

doi:10.1186/gb-2009-10-2-208

Epigenetic transmission of piRNAs through the female germline

Genome Biol. 2009 Feb 9;10(2):208. doi: 10.1186/gb-2009-10-2-208.

Authors

Sergey Shpiz¹, Alla Kalmykova

Affiliation

¹ Institute of Molecular Genetics, Russian Academy of Sciences, Kurchatov Square 2, Moscow 123182, Russia.

Abstract

In Drosophila, small RNAs bound to Piwi proteins are epigenetic factors transmitted from the mother to the progeny germline. This ensures 'immunization' of progeny against transposable elements.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Argonaute Proteins
DNA Transposable Elements
Drosophila / genetics
Drosophila Proteins / genetics*
Epigenesis, Genetic / genetics*
Female
Genomic Imprinting
Germ Cells*
RNA, Small Interfering / genetics*
RNA-Induced Silencing Complex / genetics*

Substances

Argonaute Proteins
DNA Transposable Elements
Drosophila Proteins
RNA, Small Interfering
RNA-Induced Silencing Complex
piwi protein, Drosophila