Three-dimensional source imaging from simultaneously recorded ERP and BOLD-fMRI

IEEE Trans Neural Syst Rehabil Eng. 2009 Apr;17(2):101-6. doi: 10.1109/TNSRE.2009.2015196. Epub 2009 Feb 18.

Abstract

We present the 3-D EEG source images reconstructed by using the minimum norm least square (MNLS) method in combination with the functional magnetic resonance imaging (fMRI) statistical parametric mapping. For a group of five normal subjects, electroencephalogram (EEG) and fMRI signals responding to the full-view checkerboard pattern-reversal visual stimulation were recorded simultaneously and separately. The electrical activities in V1/V2 and V5 were successfully imaged in the N75-P100-N145 and P100-N145 components, respectively. The present results demonstrate the merits of high-resolution spatiotemporal functional neuroimaging by integrating the simultaneously recorded fMRI and EEG data.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Artifacts
  • Data Interpretation, Statistical
  • Electroencephalography / methods*
  • Evoked Potentials / physiology*
  • Evoked Potentials, Visual / physiology
  • Humans
  • Image Processing, Computer-Assisted*
  • Imaging, Three-Dimensional*
  • Least-Squares Analysis
  • Magnetic Resonance Imaging / methods*
  • Male
  • Oxygen / blood*
  • Photic Stimulation
  • Young Adult

Substances

  • Oxygen