Dentistry over the last 100 years has been characterized by improved approaches to education and practice. Parallel to trends in the field of medicine as a whole, dentistry is moving toward evidence-based practices. The goal of evidence-based dentistry is the assurance, through reference to high-quality evidence, that care provided is optimal for the patient and that treatment options are presented in a manner that allows for fully informed consent. As we transition toward broad-based use of evidence-based dentistry approaches in clinical practice, many dental offices will benefit from a better understanding of how evidence-based dentistry can improve patient outcomes. This article lists the likely benefits evidence-based dentistry can provide to patients, staff, and dentists when routinely adopted in daily practice.