Background: Neisseria meningitidis is one of the major causes of meningitis in children and adolescents, but it is uncommonly found in neonatal meningitis.
Aim: to report a rare case of meningitis by Neisseria meningitides B.
Case report: We report the case of neonatal meningitis in a 20-day-old girl without shock or purpura. The symptoms were fever and seizures. The culture of cerebrospinal fluid showed to be positive for Neisseria meningitidis B. culture blood was negative. Antibiotic therapy was started at admission and maintained for 3 weeks. The outcome was favourable without neurological sequelae.
Conclusion: Early diagnosis and treatment are mandatory for life saving.