Abstract
An efficient one-pot synthesis of ethyl 2-(4-aryl-2-dialkylamino-1,3-thiazole-5-yl)-2-oxoacetates using acid chlorides, secondary amines, ethyl bromopyruvate, and ammonium thiocyanate is described.
MeSH terms
-
Amines / chemistry*
-
Chlorides / chemistry*
-
Models, Molecular
-
Pyruvates / chemistry*
-
Thiazoles / chemical synthesis*
-
Thiocyanates / chemistry*
Substances
-
Amines
-
Chlorides
-
Pyruvates
-
Thiazoles
-
Thiocyanates
-
bromopyruvate
-
thiocyanic acid