Neurologically normal people tend to collide with objects on the right side more frequently than with objects located on the left side of space. This phenomenon could be attributable to pseudoneglect wherein individuals selectively attend to the left field. The current study investigated this effect using a virtual route-following task that was presented centrally, in the lower field, and in the upper field. Handedness was also examined. Fifty-two participants (four left handed) completed this task, and when presented in the lower field, more left-side collisions emerged. In the upper condition, this bias reversed direction to the expected rightward bias. In the central condition, there was no significant directional bias in collision behavior. An interaction between handedness and presentation condition indicated that left-handed participants experienced more right-side collisions in the central condition. Collectively, these results suggest that directional biases (i.e., left vs. right) in collision behavior are modulated by both location in the visual field (central, upper, or lower) and handedness.