Enantioselective synthesis of tetrafluorinated ribose and fructose

Org Biomol Chem. 2009 Feb 21;7(4):803-14. doi: 10.1039/b817260a. Epub 2009 Jan 12.

Abstract

A perfluoroalkylidene lithium mediated cyclisation approach for the enantioselective synthesis of a tetrafluorinated aldose (ribose) and of a tetrafluorinated ketose (fructose), both in the furanose and in the pyranose form, is described.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyclization
  • Fluorine
  • Fructose / analogs & derivatives
  • Fructose / chemical synthesis
  • Ribose / analogs & derivatives
  • Ribose / chemical synthesis*
  • Stereoisomerism

Substances

  • Fluorine
  • Fructose
  • Ribose