Copper oxide nanoparticle-catalyzed coupling of diaryl diselenide with aryl halides under ligand-free conditions

Org Lett. 2009 Feb 19;11(4):951-3. doi: 10.1021/ol802734f.

Abstract

A new, efficient and ligand-free cross-coupling reaction of aryl halides and diaryl diselenides using a catalytic amount of nanocrystalline CuO as a recyclable catalyst with KOH as the base in DMSO at 110 degrees C is reported. This protocol has been utilized for the synthesis of a variety of aryl selenides in excellent yields from the readily available aryl halides and diaryl diselenides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Combinatorial Chemistry Techniques*
  • Copper / chemistry*
  • Hydrocarbons, Halogenated / chemistry*
  • Molecular Structure
  • Nanoparticles / chemistry
  • Organoselenium Compounds / chemical synthesis*
  • Organoselenium Compounds / chemistry

Substances

  • Hydrocarbons, Halogenated
  • Organoselenium Compounds
  • Copper
  • cupric oxide