Pleomorphic corneal sarcoma resembling malignant peripheral nerve sheath tumor in a horse

Vet Pathol. 2009 May;46(3):444-8. doi: 10.1354/vp.08-VP-0067-K-BC. Epub 2009 Jan 27.

Abstract

A 14-year-old Haflinger gelding presented with a protruding mass involving the cornea of the right eye. The mass was resected and submitted for histopathologic and immunohistochemical examination. The preliminary diagnosis was corneal sarcoma, most likely fibrosarcoma. The immunohistochemical results confirmed the mesenchymal origin of the neoplastic cells, which were most consistent with a malignant peripheral nerve sheath tumor. Corneal mesenchymal neoplasms are extremely uncommon tumors in human beings and domestic animals. The cause for this tumor was not determined; infection with bovine papillomavirus was not detected.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Corneal Diseases / pathology
  • Corneal Diseases / veterinary*
  • Eye Neoplasms / pathology
  • Eye Neoplasms / veterinary*
  • Horse Diseases / diagnosis
  • Horse Diseases / pathology*
  • Horses
  • Male
  • Nerve Sheath Neoplasms / diagnosis
  • Nerve Sheath Neoplasms / veterinary*
  • Sarcoma / diagnosis
  • Sarcoma / pathology
  • Sarcoma / veterinary*