Abstract
Chiral nonracemic alkynyl(alkoxy)carbene complexes of tungsten(0) undergo the [3 + 2] cyclization toward alpha-methylindoles and 1,6-dimethyl-1,2,3,4-tetrahydropyridine to provide 2,3-indoline-fused cyclopentenone and 2,3-piperidine-fused cyclopentenone skeletons, respectively, with very high enantiomeric purities (96-99% ee).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkynes / chemistry*
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Cyclopentanes / chemical synthesis*
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Indoles / chemical synthesis*
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Indoles / chemistry
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Piperidines / chemical synthesis*
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Pyridines / chemistry*
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Stereoisomerism
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Tungsten / chemistry
Substances
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Alkynes
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Cyclopentanes
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Indoles
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Piperidines
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Pyridines
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indoline
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cyclopentenone
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Tungsten