Arthroscopic elimination of monosodium urate deposition of the first metatarsophalangeal joint reduces the recurrence of gout

Arthroscopy. 2009 Feb;25(2):153-8. doi: 10.1016/j.arthro.2008.09.002.

Abstract

Purpose: To determine if the arthroscopic removal of gouty crystal deposits from the first metatarsophalangeal (MTP) joint will reduce the recurrence rate and improve foot function compared to medical treatment alone.

Methods: Twenty-eight male patients with hyperuricemia (>7.0 mg/dL) and repeated attacks of gouty arthritis of the first MTP joint were included in this study. Arthroscopic intervention of the first MTP joint was performed on 15 patients (group 1), while the other 13 patients were treated with medication alone (group 2). The follow-up period (mean +/- standard deviation) was 3.9 +/- 1.1 years in group 1 and 2.4 +/- 0.3 years in group 2.

Results: After treatment, both groups showed a significant improvement in the number of acute attacks of gouty arthritis and in their functional scores on the American Orthopaedic Foot and Ankle Society Ankle-Hindfoot Scale. On both measures, the results for group 1 were significantly better than those for group 2.

Conclusions: Arthroscopic removal of gouty crystals from the first MTP joint can reduce the rate of acute repeated attacks of gouty arthritis and increase foot and ankle function.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Arthritis, Gouty / drug therapy
  • Arthritis, Gouty / prevention & control
  • Arthritis, Gouty / surgery*
  • Arthroscopy / methods*
  • Bone Transplantation
  • Debridement / methods*
  • Follow-Up Studies
  • Gout Suppressants / therapeutic use
  • Humans
  • Hyperuricemia / complications
  • Male
  • Metatarsophalangeal Joint / chemistry
  • Metatarsophalangeal Joint / surgery*
  • Middle Aged
  • Recovery of Function
  • Recurrence
  • Severity of Illness Index
  • Uric Acid / metabolism*
  • Young Adult

Substances

  • Gout Suppressants
  • Uric Acid