Efficient solutions of cardiac membrane models using novel unsupervised clustering algorithm

Annu Int Conf IEEE Eng Med Biol Soc. 2008:2008:5910-3. doi: 10.1109/IEMBS.2008.4650560.

Abstract

We present a method to efficiently solve cardiac membrane models using a novel unsupervised clustering algorithm. The unsupervised clustering algorithm was designed to handle repeated clustering of multidimensional objects with rapidly changing properties. A Modified Trie datastructure that allowed efficient search, scalable and distributed assembly of the result was designed. The method was applied to solve monodomain models of cardiac tissue with highly non-linear reaction elements. We demonstrate the versatility and advantages of using the method by subjecting the tissue to various spatial excitation patterns.

MeSH terms

  • Action Potentials / physiology*
  • Animals
  • Artificial Intelligence*
  • Cell Membrane / physiology*
  • Cluster Analysis
  • Computer Simulation
  • Heart Conduction System / physiology*
  • Humans
  • Membrane Potentials / physiology*
  • Models, Cardiovascular*