This work presents the improvement of a software for a clinical setup, the Anesthesia Synchronization Software (ASYS). The first version presented the data acquisition from cerebral monitors and a partial control with Target Controlled Infusion (TCI) system. Based on pharmacokinetic models, the effect-site and plasma concentrations can be related with the drug dose infused and vice versa. This later version comes with the implementation of the hemodynamic monitor always present in operating rooms and with the full TCI system developed to determine the infusion rates of the drug which are given as commands to the infusion pumps.