A Bayesian hierarchical model for classifying craniofacial malformations from CT imaging

Annu Int Conf IEEE Eng Med Biol Soc. 2008:2008:4063-9. doi: 10.1109/IEMBS.2008.4650102.

Abstract

Single-suture craniosynostosis is a condition of the sutures of the infant's skull that causes major craniofacial deformities and is associated with an increased risk of cognitive deficits and learning/language disabilities. In this paper we adapt to classification of synostostic head shapes a Bayesian methodology that overcomes the limitations of our previously published shape representation and classification techniques. We evaluate our approach in a series of large-scale experiments and show performance superior to those of standard approaches such as Fourier descriptors, cranial spectrum, and Euclidian-distance-based analyses.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Bayes Theorem
  • Brain / pathology
  • Brain / physiopathology*
  • Craniosynostoses / diagnosis*
  • Craniosynostoses / physiopathology
  • Fourier Analysis
  • Humans
  • Language
  • Learning Disabilities
  • Markov Chains
  • Models, Statistical
  • Models, Theoretical
  • Reproducibility of Results
  • Skull / pathology
  • Tomography, X-Ray Computed / methods*