Sterelactones: new isolactarane type sesquiterpenoids with antifungal activity from Stereum sp. IBWF 01060

J Antibiot (Tokyo). 2008 Sep;61(9):563-7. doi: 10.1038/ja.2008.75.

Abstract

Four members of a new family of tetracyclic sesquiterenoids possessing the isolactarane skeleton have been isolated from mycelial cultures of Stereum sp. IBWF 01060. Their structure elucidation and their antifungal activity against several plant pathogens as well as other microorganisms are reported.

MeSH terms

  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification*
  • Antifungal Agents / pharmacology
  • Basidiomycota / metabolism*
  • Humans
  • Magnetic Resonance Spectroscopy
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*
  • Sesquiterpenes / pharmacology

Substances

  • Antifungal Agents
  • Sesquiterpenes
  • sterelactone A
  • sterelactone B
  • sterelactone C
  • sterelactone D