Meroditerpenoids from the southern Australian marine brown alga Sargassum fallax

Priyanka Reddy; Sylvia Urban

doi:10.1016/j.phytochem.2008.12.007

Meroditerpenoids from the southern Australian marine brown alga Sargassum fallax

Phytochemistry. 2009 Jan;70(2):250-5. doi: 10.1016/j.phytochem.2008.12.007. Epub 2009 Jan 18.

Authors

Priyanka Reddy¹, Sylvia Urban

Affiliation

¹ School of Applied Sciences (Discipline of Applied Chemistry), RMIT University, GPO Box 2476V, Melbourne, Victoria 3001, Australia.

PMID: 19155027
DOI: 10.1016/j.phytochem.2008.12.007

Abstract

Chemical investigation of the southern Australian marine brown alga Sargassum fallax resulted in the isolation of three meroditerpenoids fallahydroquinone, fallaquinone and fallachromenoic acid together with the previously reported compounds sargaquinone [isolated and identified in a mixture with sargaquinoic acid], sargahydroquinoic acid, sargaquinoic acid and sargachromenol. As a result of this study the complete 2D NMR characterisation for sargaquinoic acid and sargahydroquinoic acid can now be reported for the first time. All structures were elucidated by detailed spectrometric analysis. Sargaquinoic acid and sargahydroquinoic acid displayed moderate antitumour activity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Australia
Cell Line, Tumor
Magnetic Resonance Spectroscopy
Mice
Molecular Structure
Sargassum / chemistry*
Terpenes / chemistry*

Substances

Terpenes