Objective: To evaluate the stability of physical state with accelerate test and dropping in process before and after on compound hawthorn dropping pills.
Method: Scanning electron microscope, TG-DTA, FT-IR and XRD were used.
Result: The active components presented amorphous, tiny crystal and molecular state in dropping pills, and it had no obvious reaction between PEG 4000 and active components. With time prolonging, a little of active components changed from amorphous state to tiny crystal or molecular state.
Conclusion: Solid dispersion improved the stability and dissolution of compound hawthorn dropping pills.