Blocking VEGF as a potential approach to improve cartilage healing after osteoarthritis

J Musculoskelet Neuronal Interact. 2008 Oct-Dec;8(4):316-7.

Authors

T Matsumoto¹, G M Cooper, B Gharaibeh, L B Meszaros, G Li, A Usas, F H Fu, J Huard

Affiliation

¹ Stem Cell Research Center, Children's Hospital of Pittsburgh, Pittsburgh, PA 15213, USA. matsun@m4.dion.ne.jp

PMID: 19147955

No abstract available

Publication types

Comparative Study

MeSH terms

Animals
Bone Morphogenetic Protein 4 / genetics
Cartilage, Articular / metabolism
Cartilage, Articular / pathology*
Cartilage, Articular / physiopathology*
Chondrogenesis* / genetics
Coculture Techniques
Female
Genetic Therapy / methods
Male
Mice
Mice, Nude
Multipotent Stem Cells / metabolism
Multipotent Stem Cells / physiology
Multipotent Stem Cells / transplantation
Osteoarthritis / genetics
Osteoarthritis / pathology
Osteoarthritis / physiopathology*
Osteoarthritis / therapy*
Rats
Rats, Nude
Vascular Endothelial Growth Factor A / antagonists & inhibitors*
Vascular Endothelial Growth Factor A / biosynthesis
Vascular Endothelial Growth Factor A / genetics
Wound Healing / genetics

Substances

BMP4 protein, human
Bone Morphogenetic Protein 4
Vascular Endothelial Growth Factor A