Ocular dipping in Creutzfeldt-Jakob disease

J Neuroophthalmol. 2008 Dec;28(4):293-5. doi: 10.1097/WNO.0b013e31818e4023.

Abstract

Ocular dipping refers to a slow downward deviation of both eyes followed by a quick return to the midposition after a brief delay. Two patients with rapid neurologic deterioration in Creutzfeldt-Jakob disease (CJD) displayed ocular dipping, which quickly evolved into sustained downgaze deviation. Ocular dipping may thus be a transitional sign in a vertical gaze disturbance.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Agnosia / etiology
  • Akinetic Mutism / etiology
  • Apraxias / etiology
  • Brain / pathology*
  • Brain / physiopathology
  • Cerebral Cortex / pathology
  • Cerebral Cortex / physiopathology
  • Chromosomes, Human, Pair 20 / genetics
  • Cognition Disorders / etiology
  • Corpus Striatum / pathology
  • Corpus Striatum / physiopathology
  • Creutzfeldt-Jakob Syndrome / complications*
  • Creutzfeldt-Jakob Syndrome / pathology*
  • DNA Mutational Analysis
  • Dementia / etiology
  • Diffusion Magnetic Resonance Imaging
  • Disease Progression
  • Humans
  • Male
  • Middle Aged
  • Neurologic Examination
  • Ocular Motility Disorders / etiology*
  • Ocular Motility Disorders / pathology*
  • Ocular Motility Disorders / physiopathology
  • Perceptual Disorders / etiology
  • Positron-Emission Tomography