Compartmentalization of chemically separated components into droplets

Angew Chem Int Ed Engl. 2009;48(15):2719-22. doi: 10.1002/anie.200805396.

Abstract

Not merely a drop in the ocean: The integration of capillary electrophoresis (CE) with droplet generation driven by electroosmotic flow enabled the compartimentalization of molecular components separated by CE in a series of droplets (see picture; the green bars represent the separated analytes). The droplet-confined bands can be docked and studied on a chip.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Chromatography, High Pressure Liquid / instrumentation
  • Chromatography, High Pressure Liquid / methods
  • Electrophoresis, Capillary / instrumentation*
  • Electrophoresis, Capillary / methods
  • Fluorescence
  • Microfluidics / methods
  • Thermodynamics