[Effect of hypoxic argon-containing gas mixtures on developing organism]

Aviakosm Ekolog Med. 2008 Jul-Aug;42(4):40-3.
[Article in Russian]

Abstract

Experimental data on the impact of argon-containing hypoxic breathing mixtures on the early embryonic growth of Japanese quail (Coturnix coturnix japonica dom.) are presented. The results showed that after 4-day incubation of eggs in an oxygen-nitrogen breathing mixture (13.8-15.0% O2, 86.2-85.0% N2) only 16.7% embryos reached the stage of 3.5-d development. Introduction in the hypoxic mixture of argon (55% of the total volume) increased the number of embryos on the stage of 3.5-4 day of normal morphological development to 60%. It became evident from the analysis that embryos developed in the O2-Ar-N2 hypoxic mixture had 25% less pathologies as compared with embryos developed in a largely nitrogen-containing gas mixture. Hence, we received the experimental evidence that 55% of argon in a hypoxic breathing mixture with up to 15% of oxygen is favorable to the early embryonic growth of Japanese quail stimulating metabolic processes in germ organism.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Argon / pharmacology*
  • Coturnix / embryology*
  • Embryo, Nonmammalian / drug effects*
  • Embryo, Nonmammalian / embryology
  • Follow-Up Studies
  • Hypoxia / chemically induced
  • Hypoxia / physiopathology*
  • Nitrogen / pharmacology*

Substances

  • Argon
  • Nitrogen