Silaphenylmercuric triflate catalyzed reactions: synthesis of a solid-supported mercuric salt catalyst

Angew Chem Int Ed Engl. 2009;48(7):1244-7. doi: 10.1002/anie.200804641.

Abstract

Let it flow, let it flow: A procedure to generate the first solid-supported mercuric salt, silaphenylmercuric triflate, is described. Silaphenylmercuric triflate showed remarkable catalytic activity for an indole synthesis, furanoyne cyclization, arylyne cyclization, and tandem carbocyclizations. An efficient flow reaction system for indole synthesis and arylyne cyclization is also described (see figure).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry*
  • Catalysis
  • Cyclization
  • Heterocyclic Compounds / chemical synthesis
  • Heterocyclic Compounds / chemistry
  • Indoles / chemical synthesis*
  • Mesylates / chemical synthesis*
  • Mesylates / chemistry*
  • Organomercury Compounds / chemical synthesis*
  • Organomercury Compounds / chemistry*

Substances

  • Alkynes
  • Heterocyclic Compounds
  • Indoles
  • Mesylates
  • Organomercury Compounds
  • indole