[Nailfold capillaroscopic report: qualitative and quantitative methods]

Reumatismo. 2008 Oct-Dec;60(4):249-53. doi: 10.4081/reumatismo.2008.249.
[Article in Italian]

Abstract

Nailfold capillaroscopy (NVC) is a simple and non-invasive method used for the assessment of patients with Raynaud's phenomenon (RP) and in the differential diagnosis of various connective tissue diseases. The scleroderma pattern abnormalities (giant capillaries, haemorrages and/or avascular areas) have a positive predictive value for the development of scleroderma spectrum disorders. Thus, an analytical approach to nailfold capillaroscopy can be useful in quantitatively and reproducibly recording various parameters. We developed a new method to assess patients with RP that is capable of predicting the 5-year transition from isolated RP to RP secondary to scleroderma spectrum disorders. This model is a weighted combination of different capillaroscopic parameters (giant capillaries, microhaemorrages, number of capillaries) that allows physicians to stratify RP patients easily using a relatively simple diagram to deduce prognosis.

Publication types

  • English Abstract

MeSH terms

  • Humans
  • Microscopic Angioscopy*
  • Nails / pathology*
  • Raynaud Disease / pathology*