Abstract
Recent studies highlighting the primacy of the transcription factor network have led some researchers to question what role, if any, chromatin plays in pluripotent cells. Part of the answer may lie in its now well-established function in buffering transcriptional noise.
MeSH terms
-
Animals
-
Cell Differentiation
-
Cell Line
-
Cell Lineage
-
Chromatin / physiology*
-
Chromatin Assembly and Disassembly
-
Embryonic Stem Cells / physiology*
-
Gene Expression Regulation, Developmental
-
Nucleosomes / physiology
-
Pluripotent Stem Cells / physiology*
-
Polycomb-Group Proteins
-
Repressor Proteins / metabolism
-
Transcription Factors / metabolism
-
Transcription, Genetic*
Substances
-
Chromatin
-
Nucleosomes
-
Polycomb-Group Proteins
-
Repressor Proteins
-
Transcription Factors