A selective fluoroionophore based on BODIPY-functionalized magnetic silica nanoparticles: removal of Pb2+ from human blood

Angew Chem Int Ed Engl. 2009;48(7):1239-43. doi: 10.1002/anie.200804714.

Abstract

Get the lead out: The title fluorescence receptor exhibits a high affinity and selectivity for Pb(2+) over competing metal ions in water (see picture) with an overall emission change of approximately 8-fold at the emission maximum for Pb(2+). The fluorescence receptor can remove 96 % of 100 ppb Pb(2+) from human blood, and can be useful and effective for the selective and rapid removal of Pb(2+) in vivo.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adsorption
  • Fluorescence
  • Humans
  • Ions / analysis
  • Ions / blood
  • Lead / analysis
  • Lead / blood*
  • Magnetics*
  • Nanoparticles / chemistry*
  • Nanoparticles / ultrastructure
  • Sensitivity and Specificity
  • Silicon Dioxide / chemistry*
  • Water / chemistry

Substances

  • Ions
  • Water
  • Lead
  • Silicon Dioxide