Abstract
The trans-selective hydrosilylation of ynones (1) yields beta-silylated enones (2) that undergo a benzylic 1,4-rearrangement/cyclization reaction in the presence of base, yielding 2,5-dihydro-1,2-oxasiloles (3).
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Alkynes / chemistry*
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Benzene Derivatives / chemistry*
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Catalysis
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Combinatorial Chemistry Techniques
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Cyclization
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Ketones / chemistry*
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Molecular Structure
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Organosilicon Compounds / chemical synthesis*
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Organosilicon Compounds / chemistry*
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Stereoisomerism
Substances
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Alkynes
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Benzene Derivatives
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Ketones
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Organosilicon Compounds