Two limonoids, khayalenoids A and B with an unprecedented 8-oxa-tricyclo[4.3.2.0(2,7)]undecane motif, from Khaya senegalensis

Org Lett. 2009 Feb 5;11(3):617-20. doi: 10.1021/ol802678s.

Abstract

Two limonoids, namely khayalenoids A (1) and B (2) with an unprecedented 8-oxa-tricyclo[4.3.2.0(2,7)]undecane motif in the nortriterpenoid core, were isolated from the stems of Khaya senegalensis. Their structures with absolute configuration were determined by spectroscopic data, X-ray crystallography, and CD analysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Circular Dichroism
  • Crystallography, X-Ray
  • Limonins / chemistry*
  • Limonins / isolation & purification*
  • Meliaceae / chemistry*
  • Molecular Conformation
  • Molecular Structure
  • Plant Stems / chemistry

Substances

  • Limonins
  • khayalenoid A
  • khayalenoid B