In summary, the rapidly expanding interest in multifunctional drugs as an approach to the treatment of neurological disorders will create exciting new opportunities for the future development of novel neurotherapeutics. If robust prodromal diagnostic methodologies for the most common neurodegenerative diseases can be developed in parallel with the emergence of an array of multimodal drugs that target a reasonable selection of pathological etiologies, it is likely that significant strides will be made in the treatment of, or—even more desirable a goal—the prevention of the most common and burdensome neurological disorders.