We report the case of a woman with non-small cell lung cancer (NSCLC) metastatic to the pancreas who underwent pancreatic resection followed by a significant disease-free interval. Resection of NSCLC metastases, other than those to the brain and adrenal gland, are rarely reported. We could not identify any other cases of pancreatic metastasis resection in the literature. This case proves, in principle, that resection of solitary metastatic lesions in certain clinical conditions can be improved regardless of location.