Vertebral artery dissection: natural history, clinical features and therapeutic considerations

J Korean Neurosurg Soc. 2008 Sep;44(3):109-15. doi: 10.3340/jkns.2008.44.3.109. Epub 2008 Sep 20.

Abstract

When a tear occurs in one of the major cervicocerebral arteries and allows blood to enter the wall of the artery and split its layers, the result is either stenosis or aneurysmal dilatation of the vessel. Vertebral artery dissection (VAD) is an infrequent occurrence but is a leading cause of stroke in young and otherwise healthy patients. This article discusses recent developments in understanding of the epidemiology and pathogenesis of VAD and the various clinical manifestations, methods of diagnosis, and approaches to treatment.

Keywords: Aneurysmal dilatation; Diagnosis; Stenosis; Treatment; Vertebral artery dissection.