The association of insulin medication possession ratio, use of insulin glargine, and health benefit costs in employees and spouses with type 2 diabetes

J Occup Environ Med. 2008 Dec;50(12):1386-93. doi: 10.1097/JOM.0b013e3181875e9b.

Abstract

Objective: Measure the impact of insulin utilization on health costs and absenteeism. Compare outcomes between users of insulin glargine and other insulin.

Methods: Using a large retrospective database, this regression analysis examined annual health costs and absenteeism among employees and spouses with type 2 diabetes who used insulin. The analysis studied impacts of medication possession ratio (MPR) and glargine use, controlling for demographic factors, salary, and prior health care.

Results: Higher MPR was associated with significantly lower health costs for patients with high prior costs. Glargine users' MPR was higher than other insulin users' MPR (66% vs 54%, P < 0.0001). Among all insulin users, those using glargine had significantly lower total ($6771 vs $7969, P = 0.0046) and circulatory-specific ($312 vs $636, P < 0.0001) costs.

Conclusions: Insulin MPR and the use of insulin glargine were associated with lower health care costs.

MeSH terms

  • Absenteeism
  • Adult
  • Databases, Factual
  • Diabetes Mellitus, Type 2 / drug therapy
  • Diabetes Mellitus, Type 2 / economics*
  • Female
  • Health Benefit Plans, Employee / economics
  • Health Care Costs*
  • Humans
  • Hypoglycemic Agents / economics*
  • Hypoglycemic Agents / therapeutic use
  • Insulin / analogs & derivatives*
  • Insulin / economics*
  • Insulin / therapeutic use
  • Insulin Glargine
  • Insulin, Long-Acting
  • Male
  • Middle Aged
  • Patient Compliance / statistics & numerical data
  • Regression Analysis
  • Retrospective Studies
  • Sick Leave / economics
  • Spouses
  • United States

Substances

  • Hypoglycemic Agents
  • Insulin
  • Insulin, Long-Acting
  • Insulin Glargine