B:2a:p1.5 meningococcal strains likely arisen from capsular switching event still spreading in Spain

J Clin Microbiol. 2009 Feb;47(2):463-5. doi: 10.1128/JCM.01495-08. Epub 2008 Dec 17.

Abstract

Eighteen clustered cases of meningococcal disease associated with B:2a:P1.5 strains doubled the annual incidence up to 4.3 x 10(5) in Navarra, Spain, in 2007. Eleven percent of cases were fatalities, and 74% of cases were individuals 10 to 24 years old. This is the third cluster associated with this strain in northern Spain since 2001.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Cluster Analysis
  • DNA Fingerprinting
  • DNA, Bacterial / genetics
  • Electrophoresis, Gel, Pulsed-Field
  • Genotype
  • Humans
  • Incidence
  • Meningococcal Infections / epidemiology*
  • Meningococcal Infections / microbiology*
  • Meningococcal Infections / mortality
  • Neisseria meningitidis, Serogroup B / classification*
  • Neisseria meningitidis, Serogroup B / genetics
  • Neisseria meningitidis, Serogroup B / isolation & purification*
  • Spain / epidemiology
  • Young Adult

Substances

  • DNA, Bacterial