Efficient epoxidation of chalcones with urea-hydrogen peroxide under ultrasound irradiation

Hong Jin; Haoyu Zhao; Feihu Zhao; Shihong Li; Wei Liu; Guoping Zhou; Ke Tao; Taiping Hou

doi:10.1016/j.ultsonch.2008.10.013

Efficient epoxidation of chalcones with urea-hydrogen peroxide under ultrasound irradiation

Ultrason Sonochem. 2009 Mar;16(3):304-7. doi: 10.1016/j.ultsonch.2008.10.013. Epub 2008 Nov 7.

Authors

Hong Jin¹, Haoyu Zhao, Feihu Zhao, Shihong Li, Wei Liu, Guoping Zhou, Ke Tao, Taiping Hou

Affiliation

¹ Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, PR China.

PMID: 19084461
DOI: 10.1016/j.ultsonch.2008.10.013

Abstract

An efficient epoxidation of chalcones with urea-hydrogen peroxide (UHP) under ultrasound irradiation was carried out in 78-93% yields. Compared with the classical method, the advantages of protocol are to use a safer oxidant, mild conditions, no toxic solvent and shorter reaction time.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chalcones / chemistry*
Epoxy Compounds / chemical synthesis*
Epoxy Compounds / chemistry
Hydrogen Peroxide / chemistry*
Molecular Structure
Stereoisomerism
Ultrasonics*
Urea / chemistry*

Substances

Chalcones
Epoxy Compounds
Urea
Hydrogen Peroxide