Abstract
The key steps of a versatile new protocol for the convergent synthesis of 3,4-disubstituted indoles are the addition of an alpha-lithiated alkylaminofuran to a carbonyl compound, a microwave-accelerated intramolecular Diels-Alder cycloaddition and an in situ double aromatization reaction.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Cyclization
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Electrons
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Furans / chemistry*
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Heterocyclic Compounds / chemistry
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Indicators and Reagents
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Indoles / chemical synthesis*
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Indoles / radiation effects
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Lithium / chemistry
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Microwaves
Substances
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Furans
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Heterocyclic Compounds
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Indicators and Reagents
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Indoles
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Lithium