The use of hypertonic saline for fluid resuscitation in sepsis: a review

Crit Care Nurs Q. 2009 Jan-Mar;32(1):10-3. doi: 10.1097/01.CNQ.0000343128.81576.dd.

Abstract

Early volume resuscitation of a patient with sepsis has been shown to reduce morbidity, mortality, and healthcare resource consumption. Hypertonic saline offers a theoretically viable option for volume resuscitation. This article reviews the current information available regarding fluid resuscitation in patients with sepsis, with emphasis on the use of hypertonic saline.

Publication types

  • Review

MeSH terms

  • Animals
  • Colloids / therapeutic use
  • Critical Care / methods
  • Crystalloid Solutions
  • Disease Models, Animal
  • Drug Evaluation, Preclinical
  • Fluid Therapy / methods*
  • Humans
  • Hydroxyethyl Starch Derivatives / therapeutic use
  • Isotonic Solutions / therapeutic use
  • Patient Selection
  • Plasma Substitutes / therapeutic use
  • Plasma Volume
  • Resuscitation / methods*
  • Ringer's Lactate
  • Saline Solution, Hypertonic / pharmacology
  • Saline Solution, Hypertonic / therapeutic use*
  • Sepsis / therapy*
  • Sodium Chloride / therapeutic use
  • Treatment Outcome

Substances

  • Colloids
  • Crystalloid Solutions
  • Hydroxyethyl Starch Derivatives
  • Isotonic Solutions
  • Plasma Substitutes
  • Ringer's Lactate
  • Saline Solution, Hypertonic
  • Sodium Chloride