Abstract
Early volume resuscitation of a patient with sepsis has been shown to reduce morbidity, mortality, and healthcare resource consumption. Hypertonic saline offers a theoretically viable option for volume resuscitation. This article reviews the current information available regarding fluid resuscitation in patients with sepsis, with emphasis on the use of hypertonic saline.
MeSH terms
-
Animals
-
Colloids / therapeutic use
-
Critical Care / methods
-
Crystalloid Solutions
-
Disease Models, Animal
-
Drug Evaluation, Preclinical
-
Fluid Therapy / methods*
-
Humans
-
Hydroxyethyl Starch Derivatives / therapeutic use
-
Isotonic Solutions / therapeutic use
-
Patient Selection
-
Plasma Substitutes / therapeutic use
-
Plasma Volume
-
Resuscitation / methods*
-
Ringer's Lactate
-
Saline Solution, Hypertonic / pharmacology
-
Saline Solution, Hypertonic / therapeutic use*
-
Sepsis / therapy*
-
Sodium Chloride / therapeutic use
-
Treatment Outcome
Substances
-
Colloids
-
Crystalloid Solutions
-
Hydroxyethyl Starch Derivatives
-
Isotonic Solutions
-
Plasma Substitutes
-
Ringer's Lactate
-
Saline Solution, Hypertonic
-
Sodium Chloride