Rhodococcus equi pulmonary-central nervous system syndrome: brain abscess in a patient on high-dose steroids--a case report and review of the literature

Diagn Microbiol Infect Dis. 2009 Jan;63(1):96-9. doi: 10.1016/j.diagmicrobio.2008.08.024.

Abstract

Rhodococcus equi has emerged as an opportunistic pathogen usually causing necrotizing pneumonia in immunosuppressed patients but has been found increasingly in extrapulmonary sites. We report the 1st case of R. equi brain abscess in a patient receiving corticosteroid monotherapy and review the literature for risk factors and sites of infection.

Publication types

  • Case Reports

MeSH terms

  • Actinomycetales Infections / complications
  • Actinomycetales Infections / diagnosis*
  • Actinomycetales Infections / drug therapy
  • Adolescent
  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Inflammatory Agents / adverse effects*
  • Anti-Inflammatory Agents / therapeutic use
  • Brain / pathology
  • Brain Abscess / complications
  • Brain Abscess / diagnosis*
  • Brain Abscess / drug therapy
  • Female
  • Humans
  • Immunity, Cellular / drug effects
  • Lung Diseases, Interstitial / complications
  • Lung Diseases, Interstitial / drug therapy
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Ofloxacin / therapeutic use
  • Prednisone / adverse effects*
  • Prednisone / therapeutic use
  • Radiography, Thoracic
  • Rhodococcus equi / isolation & purification*
  • Thorax / pathology
  • Tomography, X-Ray Computed

Substances

  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Ofloxacin
  • Prednisone