Where do introns come from?

PLoS Biol. 2008 Nov 25;6(11):e283. doi: 10.1371/journal.pbio.0060283.

Abstract

The systems for mRNA surveillance, capping, and cleavage/polyadenylation are proposed to play pivotal roles in the physical establishment and distribution of spliceosomal introns along a transcript.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Codon, Nonsense / metabolism
  • DNA / genetics
  • Introns / genetics*
  • RNA Splicing
  • RNA, Messenger / metabolism*
  • Spliceosomes
  • Untranslated Regions

Substances

  • Codon, Nonsense
  • RNA, Messenger
  • Untranslated Regions
  • DNA