Assessing the bioisosterism of the trifluoromethyl group with a protease probe

ChemMedChem. 2009 Jan;4(1):49-51. doi: 10.1002/cmdc.200800321.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Barbiturates / chemical synthesis
  • Barbiturates / chemistry*
  • Barbiturates / pharmacology
  • Inhibitory Concentration 50
  • Matrix Metalloproteinase 9 / chemistry*
  • Matrix Metalloproteinase Inhibitors
  • Molecular Conformation
  • Protease Inhibitors / chemical synthesis
  • Protease Inhibitors / chemistry*
  • Protease Inhibitors / pharmacology
  • Stereoisomerism

Substances

  • Barbiturates
  • Matrix Metalloproteinase Inhibitors
  • Protease Inhibitors
  • Matrix Metalloproteinase 9