An unusual case of fungal chorioretinitis in an immunocompetent individual

Ocul Immunol Inflamm. 2008 Sep-Oct;16(5):242-3. doi: 10.1080/09273940802311769.

Abstract

Purpose: To describe a case of fungal chorioretinitis in a healthy individual.

Design: Case report.

Results: A 74-year-old immunocompetent man presented with peripheral chorioretinitis with hemorrhage in the superonasal quadrant. A retinal biopsy was performed. PAS and Gomori methenamine silver stain disclosed fungal structures identified as broad nonseptate hyphae with right-angle branches, probably belonging to the Zygomycete class. A systemic workup was initiated to seek the source of the infection with normal findings. The patient was successfully treated with intravitreous and intravenous amphotericine B.

Conclusion: Nontraumatic fungal chorioretinitis can present in immunocompetent patients.

MeSH terms

  • Aged
  • Amphotericin B / administration & dosage
  • Antifungal Agents / administration & dosage
  • Chorioretinitis / microbiology*
  • Humans
  • Immunocompetence*
  • Injections
  • Injections, Intravenous
  • Male
  • Treatment Outcome
  • Vitreous Body
  • Zygomycosis / drug therapy
  • Zygomycosis / immunology*

Substances

  • Antifungal Agents
  • Amphotericin B