Two-directional olefinic-ester ring-closing metathesis using reduced Ti alkylidenes. A rapid entry into polycyclic ether skeletons

Org Lett. 2009 Jan 1;11(1):237-9. doi: 10.1021/ol8025439.

Abstract

The use of a reduced titanium ethylidene reagent in an efficient two-directional approach to polycyclic ether skeletons is described.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Alkenes / chemistry*
  • Cyclization
  • Esters / chemistry*
  • Ethers / chemical synthesis*
  • Ethers / chemistry
  • Molecular Conformation
  • Organometallic Compounds / chemistry*
  • Polycyclic Compounds / chemical synthesis*
  • Polycyclic Compounds / chemistry
  • Stereoisomerism
  • Titanium / chemistry*

Substances

  • Alkenes
  • Esters
  • Ethers
  • Organometallic Compounds
  • Polycyclic Compounds
  • Titanium