A novel pressure-driven piezodispenser for nanoliter volumes

Rev Sci Instrum. 2008 Aug;79(8):086111. doi: 10.1063/1.2969658.

Abstract

A successful dispensing device has been built for use in biotechnology applications requiring nanoliter volume liquid transfer. Air pressure is used as the primary driving force and is controlled via a high speed miniature solenoid valve as opposed to many existing systems that use a valve in line with constantly pressurized fluid to start and stop the dispensing action. This automated pressure-driven system is used to improve a typical piezodriven microdispenser. The resulting system is much less prone to failures resulting from air entrainment and can dispense much higher viscosity fluids than the microdispenser alone.

MeSH terms

  • Atmospheric Pressure
  • Biotechnology / instrumentation*
  • Biotechnology / methods
  • Equipment Design
  • Microchemistry / instrumentation*
  • Microchemistry / methods
  • Microinjections / instrumentation*
  • Miniaturization
  • Molecular Biology / instrumentation*
  • Nanotechnology / instrumentation*
  • Nanotechnology / methods
  • Viscosity