Abstract
Ribosomal 5S RNA is the only identified target for proteins of the CTC family. All known proteins of this family, except for CTC from Aquifex aeolicus, contain a full-sized 5S rRNA-binding domain. In the present study a mistake in the published A. aeolicus genome is corrected. It has been demonstrated that the ctc gene of this organism encodes the protein with a full-length 5S rRNA-binding domain. This protein binds specifically to the bacterial 5S rRNA. Thereby, our data show that CTC A. aeolicus is not an exception from the other known CTC proteins.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Bacterial Proteins / chemistry*
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism
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Base Sequence
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Binding Sites / genetics
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Cloning, Molecular
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Genes, Bacterial
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Molecular Sequence Data
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Protein Binding / genetics
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Protein Structure, Tertiary
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RNA, Bacterial / chemistry*
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RNA, Bacterial / genetics
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RNA, Bacterial / metabolism
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RNA, Ribosomal, 5S / chemistry*
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RNA, Ribosomal, 5S / genetics
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RNA, Ribosomal, 5S / metabolism
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RNA-Binding Proteins / chemistry*
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RNA-Binding Proteins / genetics
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RNA-Binding Proteins / metabolism
Substances
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Bacterial Proteins
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RNA, Bacterial
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RNA, Ribosomal, 5S
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RNA-Binding Proteins
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protein CTC, Bacteria