Study of the correlation between clinical efficiency of impaza and serum ADMA level

Bull Exp Biol Med. 2008 Mar;145(3):367-70. doi: 10.1007/s10517-008-0093-7.

Abstract

Correlation between superlow-dose antibodies to endothelial NO synthase (Impaza) and serum level of ADMA was evaluated in a double blind placebo-controlled study. The reduction of ADMA in patients with erectile dysfunction after impaza treatment was paralleled by improvement of clinical symptoms. No clear-cut correlation between ADMA level and impaza effect was detected.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Antibodies / therapeutic use*
  • Arginine / analogs & derivatives*
  • Arginine / blood
  • Double-Blind Method
  • Erectile Dysfunction / drug therapy*
  • Humans
  • Male
  • Nitric Oxide Synthase Type III / immunology*

Substances

  • Antibodies
  • N,N-dimethylarginine
  • Arginine
  • Nitric Oxide Synthase Type III