Objective: To evaluate effect of NaFeEDTA on serum ferritin level in iron deficient epidemic population.
Methods: A comprehensive literature retrieval was performed via searching electronic databases, hand searching bibliographies of books and relevant journals, collecting grey literatures, looking into conference abstracts, contacting fields experts and reviewing references and citations. Criteria from Cochrane EPOC review group were used to assess the quality of the included studies. Generic inverse variance method was used to undertake Meta-analysis.
Results: The pooled estimate for serum ferritin level (weighted mean difference) was 1.58 microg/L (95% CI 1.20-2.09; P < 0.001).
Conclusion: This systematic review indicates that NaFeEDTA might improve serum ferritin concentration significantly in iron deficient epidemic population.