DNA methylation might be the epigenetic molecular mechanism of different antihypertensive efficacy of metoprolol in beta1-AR gene-directed therapy

Med Hypotheses. 2009 Mar;72(3):364-5. doi: 10.1016/j.mehy.2008.10.013. Epub 2008 Nov 22.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenergic beta-Antagonists / administration & dosage*
  • Antihypertensive Agents / administration & dosage*
  • DNA Methylation / drug effects
  • DNA Methylation / genetics*
  • Genetic Predisposition to Disease / genetics
  • Humans
  • Hypertension / drug therapy*
  • Hypertension / genetics*
  • Metoprolol / administration & dosage*
  • Treatment Outcome

Substances

  • Adrenergic beta-Antagonists
  • Antihypertensive Agents
  • Metoprolol