Acute hemorrhagic stroke pathophysiology and medical interventions: blood pressure control, management of anticoagulant-associated brain hemorrhage and general management principles

Fernando D Testai; Venkatesh Aiyagari

doi:10.1016/j.ncl.2008.06.001

Acute hemorrhagic stroke pathophysiology and medical interventions: blood pressure control, management of anticoagulant-associated brain hemorrhage and general management principles

Neurol Clin. 2008 Nov;26(4):963-85, viii-ix. doi: 10.1016/j.ncl.2008.06.001.

Authors

Fernando D Testai¹, Venkatesh Aiyagari

Affiliation

¹ Department of Neurology and Rehabilitation, Section of Cerebrovascular Disease and Neurological Critical Care, University of Illinois College of Medicine at Chicago, 912 South Wood Street, Room 855N, Chicago, IL 60612, USA. testai@uic.edu

PMID: 19026899
DOI: 10.1016/j.ncl.2008.06.001

Abstract

Nontraumatic intracerebral hemorrhage is a neurologic emergency that accounts for about 10% to 20% of all strokes. Few patients suffering from intracerebral hemorrhage are expected to be independent 6 months after the event. This article reviews the pathophysiology and general medical management principles of spontaneous intracerebral hemorrhage, including the acute management of elevated blood pressure and management of anticoagulant-associated intracerebral hemorrhage.

Publication types

Review

MeSH terms

Anticoagulants / therapeutic use*
Blood Pressure / drug effects
Blood Pressure / physiology*
Brain / drug effects
Brain / physiopathology
Cerebral Hemorrhage / complications
Cerebral Hemorrhage / drug therapy
Humans
Stroke / drug therapy*
Stroke / etiology

Substances

Anticoagulants