Abstract
Although inhaled nitric oxide-mediated decreases in chronic lung disease and severe intraventricular hemorrhage/periventricular leukomalacia undoubtedly contribute to improved neurodevelopmental outcomes, inhaled nitric oxide has an independent neuroprotective effect. Although these data are encouraging, additional studies are required before recommending the routine use of inhaled nitric oxide for neuroprotection in preterm infants.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Administration, Inhalation
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Central Nervous System Diseases / prevention & control*
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Heart / drug effects
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Humans
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Infant, Newborn
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Infant, Premature*
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Lung / drug effects
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Nervous System / drug effects
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Nervous System / growth & development
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Neuroprotective Agents / administration & dosage*
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Neuroprotective Agents / therapeutic use
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Nitric Oxide / administration & dosage*
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Nitric Oxide / therapeutic use
Substances
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Neuroprotective Agents
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Nitric Oxide