Investigation of C/EBPalpha function in human (versus murine) myelopoiesis provides novel insight into the impact of CEBPA mutations in acute myelogenous leukemia (AML)

Leukemia. 2009 May;23(5):978-83. doi: 10.1038/leu.2008.332. Epub 2008 Nov 20.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • CCAAT-Enhancer-Binding Proteins / antagonists & inhibitors
  • CCAAT-Enhancer-Binding Proteins / physiology*
  • Cell Differentiation
  • Colony-Forming Units Assay
  • Dimerization
  • Humans
  • Leukemia, Myeloid, Acute / genetics*
  • Leukemia, Myeloid, Acute / metabolism
  • Mice
  • Mutation / genetics*
  • Myeloid Cells / metabolism
  • Myelopoiesis / physiology*
  • RNA, Small Interfering / pharmacology
  • Stem Cells / metabolism

Substances

  • CCAAT-Enhancer-Binding Proteins
  • CEBPA protein, human
  • CEBPA protein, mouse
  • RNA, Small Interfering