Autofluorescence imaging of pingueculae

Br J Ophthalmol. 2009 Mar;93(3):396-9. doi: 10.1136/bjo.2008.144055. Epub 2008 Nov 19.

Abstract

Aims: To analyse the autofluoresence (AF) properties of pingueculae and compare the size of AF with the extent of the visible lesion.

Methods: Forty eyes of 23 patients with pingueculae were included in the study. AF images were obtained using an HRA2 confocal scanning laser ophthalmoscope; anterior segment photographies were obtained using TRC-50IX, IMAGEnet 2000 Digital Imaging System. The AF characteristics of pingueculae were analysed. The extent of visible lesion in anterior segment photography and AF image was compared.

Results: AF images revealed well-defined hyper-autofluorescence in the area of pinguecula, which was greater than the extent of visible pinguecula in the slit-lamp examination, in 40 of 56 lesions (71.4%). In none of the eyes was the hyperautofluorescent area smaller than the extent of visible lesion.

Conclusion: Pingueculae display hyperautofluorescence in AF imaging. The real size of pingueculae may be estimated by its AF characteristics, which is mostly larger than the visible lesion.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Conjunctival Diseases / pathology*
  • Female
  • Fluorescence
  • Fundus Oculi
  • Humans
  • Lipofuscin / physiology
  • Male
  • Microscopy, Confocal
  • Middle Aged
  • Ophthalmoscopy
  • Photography
  • Pigment Epithelium of Eye / pathology*

Substances

  • Lipofuscin