Intranodal palisaded myofibroblastoma; a case report and review of the literature

Pathol Oncol Res. 2009 Jun;15(2):297-300. doi: 10.1007/s12253-008-9122-0. Epub 2008 Nov 8.

Abstract

Intranodal palisaded myofibroblastoma (IPM) also called as intranodal hemorrhagic spindle cell tumor with amianthoid fibers is a distinctive and rare mesenchymal neoplasm of lymph nodes. This entity generally misdiagnosed as intranodal Kaposi's sarcoma or schwannoma in past. In contrast to Kaposi's sarcoma, it behaves in a benign fashion and does not need any further therapy except total surgical resection of the mass. This neoplasm has a great predilection for the inguinal region. The lesion presents typically as a unilateral, painless, solitary mass. To our knowledge, approximately 53 cases of IPM have been reported in the English-language literature. We present a 43-year-old-male patient with IPM and discuss histological, immunohistochemical features and pathogenesis of this rare benign neoplasm.

Publication types

  • Review

MeSH terms

  • Adult
  • Biomarkers, Tumor / metabolism
  • Carcinoma / metabolism
  • Carcinoma / pathology*
  • Humans
  • Immunoenzyme Techniques
  • Lymph Nodes / metabolism
  • Lymph Nodes / pathology*
  • Male
  • Neoplasms, Muscle Tissue / metabolism
  • Neoplasms, Muscle Tissue / pathology*

Substances

  • Biomarkers, Tumor